If research questions are controlled, are the other things predetermined?

To an extent, yes.

This is an important refinement.

Suppose an institution determines:

“Researchers may investigate only Question A.”

Then:

Question selection is controlled.

That substantially constrains:

methods;

evidence;

possible findings;

conclusions.

But it still does not necessarily predetermine the conclusion.

For example:

Question: “Does Policy X improve economic growth?”

Researchers may be required to investigate that question.

But the evidence could show:

Yes.

or:

No.

So controlling the question constrains the universe of possible knowledge, but does not necessarily dictate the answer.